Nanoparticle material could prevent hospital infection

21 February 2018

21 Feb 2018 

Antibiotics are often given to hospital patients, even following the most routine operations, to counter the risk of bacterial infections and viruses.

Now, materials scientists at the University of Manchester have developed a 'durable and washable, concrete-link' composite material that boasts antibacterial properties, with the aim of binding the material to doctors', nurses' and healthcare professionals' uniforms.

Bacterial infection is a major issue in hospitals across the UK, and is known to spread via surfaces and clothing. E. coli infections alone killed more than 5,500 NHS patients in 2015, and the UK government estimates the cost of such infections to the NHS at £2.3 billion this year alone.

But doctors, nurses and healthcare professionals could soon be wearing uniforms brushed with tiny copper nanoparticles to reduce the spread of bacterial infections and viruses. Working in collaboration with universities in China, the Manchester team created the composite material using antibacterial copper nanoparticles.

They have also developed a way to bind the composite to wearable materials such as cotton and polyester - a stumbling block for scientists in the past.

Precious metals, such as gold and silver, have excellent antibacterial and antimicrobial properties, but their commercial use in textiles is prohibitive due to extremely high costs. That means copper is the material of choice for researchers, as it has very similar antibacterial properties to gold and silver but is much cheaper.

Using a process called polymer surface grafting, the research team tethered copper nanoparticles to cotton and polyester using a polymer brush, creating a strong chemical bond. The researchers claim this bond creates excellent washable properties and , and could see copper-covered uniforms and textiles commercialised in the future.

'Now that our composite materials present excellent antibacterial properties and durability, it has huge potential for modern medical and healthcare applications,' Lead author, Dr Xuqing Liu, said.

The researchers tested their copper nanoparticles on cotton as it is used more widely than any other natural fibre and polyester as it is a typical polymeric, manmade material. Each material was brushed with the tiny copper nanoparticles, which measure between 1-100 nanometres (nm). 100nm is the equivalent to just 0.0001 millimetres (mm) - a human hair is approximately 90,000nm wide.

The team found their cotton and polyester coated-copper fabrics showed excellent antibacterial resistance against Staphylococcus aureus (S. aureus) and E. coli, even after being washed 30 times.

Dr Liu said, 'These results are very positive, and some companies are already showing interest in developing this technology. We hope we can commercialise the advanced technology within a couple of years. We have now started to work on reducing cost and making the process even simpler.'

DOI: 10.1155/2018/6546193

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