27 February 2014

Catalytic C-H bond functionalization - a new paradigm for molecular synthesis

Organised by:

SCI's Thames and Kennet Regional Group

Charterhouse School, Godalming

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This talk will be delivered by Professor Matthew Gaunt of the University of Cambridge.

The syntheses of the molecules that we need for everyday life, such as medicines and functional materials, are almost always sourced from feedstock chemicals that comprise arenes, alkanes, alkenes, alkynes, alcohols, amines, and carbonyl containing compounds.

Notwithstanding the remarkable advances of over 100 years of ‘modern’ chemical synthesis, the last 30 years has witnessed a revolution in the way molecules are made as a result of the advent of catalysis. In particular, by using metals such as palladium, ruthenium, rhodium, and copper, transition metal catalysis has contributed some of the most powerful
activation modes for standard chemical feedstocks, contributing a plethora of new transformations to the synthetic chemists toolbox.

Palladium has proven to be a remarkably adaptable metal catalyst owing to its capacity to shuttle between the Pd(0) and Pd(II) oxidation states. We were inspired by (a) the diverse reactivity displayed by organopalladium complexes in the Pd(II) oxidation state, and (b) whether other metals could offer such broad reactivity over two interchangeable oxidation states. This lecture will cover aspects of these research areas focused on C-H bond functionalization using Pd(II)-catalysts.

Venue and Contact

University of Cambridge

Room 105, Charterhouse School, 
Charterhouse, Godalming, GU7 2DX 


Oliver Choroba

Tel: 01483 291713

Email: owc@charterhouse.org.uk


This is a FREE event - early booking is advised

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