Process Development is the application of chemistry to the scale up of new synthetic processes from the laboratory, through pilot plant to full scale commercial manufacture and into life cycle management. It is an extremely broad discipline, crossing the boundaries between synthetic organic chemistry, process technology and chemical engineering.
The area of Process Development continues to be a challenging and important area for the research into and application of modern synthetic organic chemistry, as well as enabling technologies.
The symposium aims to bring together a wide range of speakers from across the Pharmaceutical, Agrochemical and Fine Chemical industries, as well as from an academic background. This meeting brings together experts from across the entire spectrum of the discipline to present state of the art process development. As an established and well attended meeting, the process development symposium offers an excellent opportunity for networking between like-minded process scientists of all levels of experience and from all areas of the chemical industry.
Day 1 - 11th April 2018
- Registration and refreshments
- Lunch and exhibition Please note: Bedrooms at the college will be available from 14:00 onwards CHAIR: Dr Alan Robinson, Syngenta, Switzerland
- Opening remarks
- Developing, understanding and incorporating photomediated transformations in pharmaceutical development Dr Danielle Schultz, Merck Sharp and Dohme, USA
- C-H functionalisation: oxidative carbon-heteroatom bond formation using base metal catalysis and oxygen Prof Bert Maes, University of Antwerp, Belgium
- Use of sponge metal catalysts for the continuous hydrogenation of an aliphatic nitro group Dr Glynn Williams, GlaxoSmithKline, UK
- Refreshment break and exhibition CHAIR: Dr David Lathbury, Astute Chemical Development Consulting Ltd, UK
- Enabling preparation and use of dibromoformaldoxime via continuous processing Dr Edouard Godineau, Syngenta, Switzerland
- Monitoring chemical changes during food sterilisation Dr James Marshall, Mars Petcare, UK
- Closing remarks
- Wine reception (sponsored by Chrialquest) and exhibition
- Dinner for residents (Churchill college dining hall)
Day 2 - 12th April 2018
- Catalytic asymmetric dearomatization (CADA) reactions Prof Shu-Li You, Shanghai Institute of Organic Chemistry, (SIOC), China
- The manufacture of a process surprises during the development of an aliskiren intermediate Dr Thomas Allmendinger, Novartis, Switzerland
- Refreshment break and exhibition CHAIR: Mr Robert Walton, Pfizer Ltd, UK
- Process development challenges in the manufacture of synthetic peptides Dr Alastair Hay, Almac, UK
- Fluorination technology development in the agrichemical industry Dr Linhua Wang, Syngenta, USA
- Lunch and exhibition CHAIR: Dr David Pascoe, GlaxoSmithKline, UK
- Case study - Safety Dr Andy Payne, GlaxoSmithKline, UK
- Potent compound manufacturing at pilot plant scale. Development of a method for production of the cytostatic agent melflufen Dr Johan Wennerberg, Magle Chemoswed, Sweden
- Refreshment break and exhibition CHAIR: Dr Louis Diorazio, AstraZeneca, UK
- Large-scale manufacturing of the PI3K beta-sparing inhibitor taselisib Dr Remy Angelaud, Genentech, USA
- AstraZeneca, GlaxoSmithKline, Pfizer & Syngenta prize for process chemistry research 2018 Selective Direct Fluorination Strategies Prof Graham Sandford, Durham University
- Closing remarks
- Wine Reception (sponsorsed by Johnson Matthey) and exhibition
- Symposium dinner (Churchill college dining hall)
Day 3 - 13th April 2018
- Development of a sustainable and scalable process for step 1 and 2 of talazoparib tosylate Mr Craig Knight, Pfizer, UK
- Development of a commercial route to the reversible BTK inhibitor BMS-986142-01 Dr Steven Wisniewski, BMS, USA
- Refreshment break and exhibition CHAIR: Dr Andy Wells, Charnwood Technical Consulting Ltd, UK
- Lesinurad - following the science to a treatment for Gout Dr Alexandra Parker, AstraZeneca, UK
- Case Study Dr John Pavey, UCB, UK
- Symposium close
Venue and Contact
Early bird fees before Friday 26 January 2018
GB£370 . . . . . . . . . . . . . . . . . SCI Member
GB£255 . . . . . . . . . . . . . . . . . SCI Subsidised Member
GB£400 . . . . . . . . . . . . . . . . . Non-Member
Standard fees after Friday 26 January 2018
GB£540 . . . . . . . . . . . . . . . . SCI Member
GB£280 . . . . . . . . . . . . . . . . SCI Subsidised Member
GB£595 . . . . . . . . . . . . . . . . Non-Member
SCI Platinum Corporate Members receive 25% off the above rates
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